【学歴】
星薬科大学薬学部卒業
星薬科大学大学院薬学研究科 修士（薬学）
星薬科大学大学院薬学研究科 博士（薬学）

【職歴】
川崎医科大学薬理学教室助教、講師を経て現職

【学会活動】
日本薬理学会評議員 (薬理学エデュケーター)、日本神経精神薬理学評議員、日本アルコール・アディクション医学会評議員、日本ストレス学会評議員

【受賞暦】
第35回日本ストレス学会学術総会　奨励賞 (高田賞)

薬剤師、薬理学エデュケーター(日本薬理学会)

神経精神薬理学、行動薬理学、薬物依存

【researchmap】
https://researchmap.jp/30454846

• 1. Miyagishi H, Tsuji M, Miyagawa K, Kurokawa K, Mochida-Saito A, Takahashi H, Kosuge Y, Ishige K, Takeda H: Possible role of transcriptional regulation of 5-HT1A receptor in the midbrain on unadaptation to stress in mice. Brain Research. 査読有 1783:147859 2022
  2. Takahashi K, Kurokawa K, Hog L, Miyagawa K, Mochida-Saito A, Iwasa M, Iwasa H, Nakagawasai O, Tadano T, Takeda H, Tsuji M: Antidepressant effects of Enterococcus faecalis 2001 through the regulation of prefrontal cortical myelination via the enhancement of CREB/BDNF and NF-kBp65/LIF/STAT3 pathways in olfactory bulbectomize mice. J Psychiatr Res. 査読有 148:137-148 2022
  3. Kimijima H, Miyagawa K, Kurokawa K, Mochida-Saito A, Takahashi H, Takeda H, Tsuji M: Trichostatin A, a histone deacetylase inhibitor, alleviates the emotional abnormality induced by maladaptation to stress in mice. Neuroscience Letters. 査読有 766:136340 2022
  4. Kurokawa K, Takahashi H, Miyagawa K, Mochida-Saito A, Takeda H, Tsuji M: Activation of 5-HT1A receptor reduces abnormal emotionality in stress-maladaptive mice by alleviating decreased myelin protein in the ventral hippocampus. Neurochem Int. 査読有 151:105213 2021
  5. Akai H, Miyagawa K, Takahashi K, Mochida-Saito A, Kurokawa K, Takeda H, Tsuji M, Sugawara H, Yasaka K, Kunimatsu A, Inoue Y, Abe O, Ohtomo K, Kiryu S: Effects of gadolinium deposition in the brain on motor or behavioral function: a mouse model. Radiology. 査読有 301: 409-416 2021
  6. Takahashi K, Kurokawa K, Hog L, Miyagawa K, Mochida-Saito A, Takeda H, Tsuji M: Disturbance of prefrontal cortical myelination in olfactory bulbectomized mice is associated with depressive-like behavior. Neurochem Int. 査読有 148:105112 2021
  7. Takahashi K, Tsuji M, Nakagawasai O, Katsuyama S, Miyagawa K, Kurokawa K, Mochida-Saito A, Iwasa M, Iwasa H, Takeda H, Tadano T: Activation of cholinergic system partially rescues olfactory dysfunction-induced learning and memory deficit in mice. Behavioural Brain Research. 査読有 408:113283 2021
  8. Kurokawa K, Tsuji M, Takahashi H, Miyagawa K, Mochida-Saito A, Takeda H: Leukemia inhibitory factor participates in the formation of stress adaptation via hippocampal myelination in mice. Neuroscience. 査読有 446:1-13 2020
  9. Takahashi K, Kurokawa K, Miyagawa K, Mochida-Saito A, Nemoto Y, Iwasa H, Nakagawasai O, Tadano T, Takeda H, Tsuji M: Enterococcus faecalis 2001 improves memory-related behaviors by enhancement of hippocampal neurogenesis via ERK/CREB/BDNF pathway in olfactory bulbectomized mice. Physiology Behavior. 査読有 223:112997 2020
  10. Takahashi K, Nakagawasai O, Nakajima T, Okubo M, Nishimura Y, Sakuma W, Yamagata R, Nemoto W, Miyagawa K, Kurokawa K, Mochida-Saito A, Tsuji M, Takeda H, Tadano T, Tan-No K: Dopmaine D2 receptor supersensitivity in the hypothalamus of olfactory bulbectomized mice. Brain Research. 査読有 1746:147015 2020
  11. Miyagishi H, Tsuji M, Miyagawa K, Kurokawa K, Mochida-Saito A, Takahashi H, Ishige K, Takeda H: Characterization of 5-HT1A receptor and transport protein KIF13A expression in the hippocampus of stress-adaptive and -maladaptive mice. Neuroscience Letters. 査読有 733:135082 2020
  12. Ohno R. Miyagishi H, Tsuji M, Saito A, Miyagawa K,Kurokawa K, Takeda H: Yokukansan, a traditional Japanese herbal medicine, enhances the anxiolytic effect of fluvoxamine and reduces cortical 5-HT2A receptor expression in mice. Journal of Ethnopharmacology査読有 216:89-96. 2018
  13. Saito A, Miyagawa K, Miyagishi H, Kurokawa K, Umeda A, Okada Y, Tsuji M, Takeda H: Possible involvement of monoamine neurons in the emotional abnormality in Kir6.2-deficient mice. Physiology and Behavior査読有 188: 251-261. 2018
  14. Mizuno K,Kurokawa K, Ohkuma S Nicotinic acetylcholine receptors regulate type 1 inositol 1,4,5-trisphosphate receptor expression via calmodulin kinase IV activation. J Neurosci Res査読有 93,660-665. 2015
  15. Kurokawa K, Mizuno K, Ohkuma S: Increase of type 2 ryanodine receptors in mouse nucleus accumbens in the development and expression of morphine-induced place preference. J Pharmacol Sci. 査読有 126(3):285-290. 2014
  16. Kurokawa K, Mizuno K, Ohkuma S: Sensitization of ethanol-induced place preference as result of up-regulation of type 1 inositol 1,4,5-trisphosphate receptors in mouse nucleus accumbens. J Neurochem. 査読有 131(6):836-847. 2014
  17. Kurokawa K, Mizuno K, Ohkuma S: Dopamine D1 receptor signaling system regulates ryanodine receptor expression in ethanol physical dependence. Alcohol Clin Exp Res査読有37:771-783. 2013
  18. Kurokawa K, Mizuno K, Ohkuma S: Possible involvement of type 1 inositol 1,4,5-trisphoshate receptors up-regulated by dopamine D1 and D2 receptors in mouse nucleus accumbens neurons in the development of methamphetamine-induced place preference. Neuroscience. 査読有 227:22-29. 2012.
  19. Kurokawa K, Mizuno K, Kiyokage E, Shibasaki M, Toida K, Ohkuma S: Dopamine D1 receptor signaling system regulates ryanodine receptor expression after intermittent exposure to methamphetamine in primary cultures of midbrain and cerebral cortical neurons. J Neurochem. 査読有118:773-783. 2011
  20. Kurokawa K, Mizuno K, Shibasaki M, Ohkuma S:Regulation of ryanodine receptors by dopamine D1 receptors during methamphetamine-induced place conditioning. J Neurochem. 査読有 115: 1206-1214. 2010.